Reaktion #95222

Reaktionsgleichung

5-amino-3-trichloromethyl-1,2,4-thiadiazole

2,6-dichlorobenzoyl chloride

→

pure product

Ausbeute 22.0%

5-(2,6-Dichlorobenzamido)-3-Trichloromethyl-1,2,4-Thiadiazole

Ausbeute 22.0%

Lösungsmittel

dichlorobenzene

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationAfter filtration
2. 2
   Sonstigethe crude product precipitated from the filtrate
3. 3
   SonstigeRecrystallization from toluene

Vorschrift

A solution of 22.0 g (0.1 mole) 5-amino-3-trichloromethyl-1,2,4-thiadiazole and 20.1 g (0.1 mole) 2,6-dichlorobenzoyl chloride was refluxed for 8 hours in 200 ml dichlorobenzene. After filtration, the crude product precipitated from the filtrate upon standing. Recrystallization from toluene gave 8.6 g (22% yield) of pure product; m.p. 209° C.

Quelle