Reaktion #950048

Reaktionsgleichung

4-Decylphenylnitromethane

ethanol

sodium hydroxide

formalin

→

2-(4-Decylphenyl)-2-nitro-1,3-propanediol

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.DISTILLATIONThe solvent was distilled away
2. 2
   Extraktionthe residue was extracted with ethyl acetate
3. 3
   WaschenThe extract was washed with saturated brine
4. 4
   Trocknendried over anhydrous sodium sulfate
5. 5
   workup.DISTILLATIONThe solvent was distilled away
6. 6
   Sonstigethe residue was crystallized from hexane
7. 7
   Sonstigeto give 1.75 g of the colorless, scale-like subject compound

Vorschrift

4-Decylphenylnitromethane (555 mg) was dissolved in ethanol (5 ml) and thereto were added a 1N aqueous sodium hydroxide solution (0.02 ml) and 37% formalin (0.45 ml). The mixture was heated at 50° C. for 6 hours. The solvent was distilled away and the residue was extracted with ethyl acetate. The extract was washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was distilled away and the residue was crystallized from hexane to give 1.75 g of the colorless, scale-like subject compound.

Quelle