Reaktion #94898

Reaktionsgleichung

1-methyldecylamine

3-phenyl-3-(4-nitrophenyl)propenoic acid

ethyl chloroformate

→

title compound

Ausbeute 51.0%

N-(1-Methyldecyl)-3-phenyl-3-(4-nitrophenyl)propenamide

Ausbeute 51.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigesubstantially according to the procedure of Preparation 21
2. 2
   SonstigeThe solid was recrystallized from hexane
3. 3
   Sonstigegiving a small amount of material which
4. 4
   SonstigeThe mother liquors were evaporated in vacuo
5. 5
   Sonstigeto give an oil which
6. 6
   FiltrationThe solid was filtered off

Vorschrift

The title compound was prepared from 3-phenyl-3-(4-nitrophenyl)propenoic acid via mixed anhydride formation using ethyl chloroformate, followed by reaction with 1-methyldecylamine, substantially according to the procedure of Preparation 21. The product was induced to solidify by trituration under hexane. The solid was recrystallized from hexane, giving a small amount of material which was discarded. The mother liquors were evaporated in vacuo to give an oil which solidified when stirred under acetonitrile. The solid was filtered off, giving a 51% yield of the title compound, m.p. 69°-71° C.

Quelle