Reaktion #94887

ord-3b2fef9249ba4fb9b8c9f123edf9d8cb

Reaktionsgleichung

CCCC(=O)c1ccc(OCCN(CC)CC)cc1Cl
2-diethylaminoethyl chloride hydrochloride
CCCC(=O)c1ccc(OCCN(CC)CC)cc1Cl
1-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-1-butanone
Cl.ClCCN1CCCC1
N-(2-chloroethyl)pyrrolidine hydrochloride
CCCC(=O)c1ccc(OCCN2CCCC2)cc1Cl
1-{2-Chloro-4-[2-(N-pyrrolidinyl)ethoxy]-phenyl}-1-butanone

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThis compound is prepared by essentially the same procedure
  2. 2
    SonstigeThe product is obtained as a pale yellow oil upon distillation in vacuo (0.3 mm.)

Vorschrift

This compound is prepared by essentially the same procedure as described in Example 1 Step A except that the 2-diethylaminoethyl chloride hydrochloride of Example 1 Step A is replaced by an equimolecular quantity of N-(2-chloroethyl)pyrrolidine hydrochloride. The product is obtained as a pale yellow oil upon distillation in vacuo (0.3 mm.).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04342782uspto-grants-1982_08