Reaktion #94840

Reaktionsgleichung

phenyl isothiocyanate

triethylamine

1,3-dimethyl-2-imino-imidazolidine hydrobromide

→

N-(1,3-dimethyl-2-imidazolidinylidene)-N'-phenyl-thiourea

Lösungsmittel

chloroform

chloroform

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe reaction mixture is refluxed for 15 hours
2. 2
   TemperaturAfter cooling
3. 3
   Waschenit is washed with water
4. 4
   Trocknendried over sodium sulfate
5. 5
   Sonstigeevaporated in vacuo

Vorschrift

30.4 g (0.3 mol) of triethylamine are added to a suspension of 58.2 g (0.3 mol) of 1,3-dimethyl-2-imino-imidazolidine hydrobromide in 470 ml of chloroform, at 5°, with stirring. A solution of 40.6 g (0.3 mol) of phenyl isothiocyanate in 235 ml of chloroform is then added dropwise and the reaction mixture is refluxed for 15 hours. After cooling, it is washed with water, dried over sodium sulfate and evaporated in vacuo. Crude N-(1,3-dimethyl-2-imidazolidinylidene)-N'-phenyl-thiourea is obtained and after recrystallisation from ethanol this melts at 195°-196°.

Quelle