Reaktion #94654

Reaktionsgleichung

sulfuric acid

nitric acid

4-hydroxypyridine nitrate

→

3-nitro-4-pyridone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas heated on a steam bath for 21/4 hours
2. 2
   TemperaturIt was cooled
3. 3
   SonstigeThe resulting precipitate was collected on a filter
4. 4
   Waschenwashed with a minimum of water
5. 5
   Sonstigerecrystallized from water

Vorschrift

To a cold solution of 35 ml. of fuming sulfuric acid and 45 ml. of fuming nitric acid was added 35 grams of the 4-hydroxypyridine nitrate. After allowing the mixture to warm to room temperature over night it was heated on a steam bath for 21/4 hours. It was cooled and poured onto 500 grams of ice. The resulting precipitate was collected on a filter, washed with a minimum of water and recrystallized from water to give 3-nitro-4-pyridone, m.p. 282-284° C.

Quelle