Reaktion #94634

Reaktionsgleichung

2-(3-aminophenyl)oxazolo[4,5-b]pyridine

pyridine

acetic anhydride

→

2-(3-acetamidophenyl)oxazolo[4,5-b]pyridine

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONwas diluted to 50 ml
2. 2
   workup.STIRRINGAfter stirring a short time
3. 3
   Temperaturcooling
4. 4
   Sonstigethe precipitate was collected
5. 5
   Waschenwashed with water
6. 6
   Sonstigedried
7. 7
   SonstigeRecrystallization from ethyl acetate

Vorschrift

A solution of 0.63 g. of 2-(3-aminophenyl)oxazolo[4,5-b]pyridine in 10 ml. of pyridine was treated with 0.35 ml. of acetic anhydride with stirring. After stirring over the weekend the mixture was diluted to 50 ml. with water. After stirring a short time and cooling, the precipitate was collected, washed with water and dried. Recrystallization from ethyl acetate gave 2-(3-acetamidophenyl)oxazolo[4,5-b]pyridine, m.p. 201.5-202.5.

Quelle