Reaktion #94563

Reaktionsgleichung

ethyl 3,4-dichlorophenylacetate

N-bromosuccinimide

benzoyl peroxide

→

ethyl α-bromo-3,4-dichlorophenylacetate

Lösungsmittel

carbon tetrachloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeIn a three-necked flask fitted with a Nichrome stirrer and a reflux condenser
2. 2
   TemperaturThe reaction mixture is heated
3. 3
   Temperaturat reflux for 18 hours
4. 4
   Temperaturcooled
5. 5
   Filtrationfiltered
6. 6
   EinengenThe carbon tetrachloride filtrate is concentrated under reduced pressure
7. 7
   Sonstigeto give a deep orange liquid
8. 8
   workup.DISTILLATIONVacuum distillation at 115°-120° C. (0.5 mm)

Vorschrift

In a three-necked flask fitted with a Nichrome stirrer and a reflux condenser is placed 7.0 g of ethyl 3,4-dichlorophenylacetate, 5.9 g of N-bromosuccinimide, 0.1 g of benzoyl peroxide and 150 ml of carbon tetrachloride. The reaction mixture is heated at reflux for 18 hours, cooled and filtered. The carbon tetrachloride filtrate is concentrated under reduced pressure to give a deep orange liquid. Vacuum distillation at 115°-120° C. (0.5 mm) gives ethyl α-bromo-3,4-dichlorophenylacetate as a pale yellow liquid.

Quelle