Reaktion #94534

ord-aa1ff7459091416091a05f41aeeacace

Reaktionsgleichung

Nc1ccc(C(=O)O)c(C(=O)O)c1
4-aminophthalic acid
[Na][Na]
disodium
Nc1cccc(C(=O)O)c1C(=O)O
3-aminophthalic acid
[Na][Na]
disodium
→
CC1=C(C)C(=O)N(c2ccc3c(c2)C(=O)OC3=O)C1=O
4-(dimethylmaleinimidyl)-phthalic anhydride

Edukte

Nc1ccc(C(=O)O)c(C(=O)O)c1
4-aminophthalic acid
[Na][Na]
disodium
Nc1cccc(C(=O)O)c1C(=O)O
3-aminophthalic acid
[Na][Na]
disodium

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

If instead of 22.5 g of the disodium salt of 3-aminophthalic acid, an equivalent amount of the disodium salt of 4-aminophthalic acid is employed and in other respects the procedure indicated in the above example is followed, 4-(dimethylmaleinimidyl)-phthalic anhydride of melting point 197° C. is obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04131613uspto-grants-1978_12