Reaktion #94510

Reaktionsgleichung

end product

8-Chloro-6-phenyl-4H-pyrazolo[1,5-a][1,4]benzodiazepine-2-carboxylic acid, methyl ester

mono-methylamine

→

desired product

8-Chloro-N-methyl-6-phenyl-4H-pyrazolo[1,5-a][1,4]benzodiazepine-2-carboxamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThis compound was prepared from 1.48 g
2. 2
   SonstigeRecrystallization from acetone/ether/hexane

Vorschrift

This compound was prepared from 1.48 g. (4.2 mmol) of the end product of Example 9 and mono-methylamine according to the procedure described above in Example 11. Recrystallization from acetone/ether/hexane gave the desired product, mp 170°-172°. An analytical sample was prepared by recrystallization from the same solvent system and isolated as colorless needles: mp 170°-172°.

Quelle