Reaktion #94412

Reaktionsgleichung

2-(4-amino-5-oxo-1,3,6-cycloheptatrien-1-ylamino)-2-butenedioic acid diethyl ester

acetic anhydride

→

2-(4-acetylamino-5-oxo-1,3,6-cycloheptatrien-1-ylamino)-2-butenedioic acid diethyl ester

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solution is evaporated
2. 2
   workup.DISSOLUTIONthe residue is dissolved in ethyl acetate
3. 3
   WaschenThe solution is washed with 1N potassium hydroxide and water
4. 4
   Trocknendried over sodium sulfate
5. 5
   Sonstigeevaporated

Vorschrift

A solution of 2-(4-amino-5-oxo-1,3,6-cycloheptatrien-1-ylamino)-2-butenedioic acid diethyl ester (1.7 g, described in Example 1) in acetic anhydride (17 ml) is stirred at room temperature for 16 hr. The solution is evaporated and the residue is dissolved in ethyl acetate. The solution is washed with 1N potassium hydroxide and water, dried over sodium sulfate and evaporated to give a residue of 2-(4-acetylamino-5-oxo-1,3,6-cycloheptatrien-1-ylamino)-2-butenedioic acid diethyl ester.

Quelle