Reaktion #943991

ord-df40f5629bfe4f319cce850396b9ef9b

Reaktionsgleichung

COc1ccc2c(c1O)CCCC2=O
5-hydroxy-6-methoxy-1-tetralone
BrCc1ccccc1
benzyl bromide
O=C([O-])[O-].[K+].[K+]
K2CO3
→
COc1ccc2c(c1OCc1ccccc1)CCCC2=O
title product
COc1ccc2c(c1OCc1ccccc1)CCCC2=O
5-Benzyloxy-6-methoxy-3,4-dihydro-2H-naphthalen-1-one

Edukte

COc1ccc2c(c1O)CCCC2=O
5-hydroxy-6-methoxy-1-tetralone
BrCc1ccccc1
benzyl bromide
O=C([O-])[O-].[K+].[K+]
K2CO3

Reagenzien

Keine

Lösungsmittel

CC(C)=O
acetone

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Using a procedure analogous to Example 7 from 4.5 g (0.024 mole) of 5-hydroxy-6-methoxy-1-tetralone, 5.4 g (0.031 mole) of benzyl bromide and 10 g (0.072 mole of K2CO3 in 100 ml of acetone), the title product was obtained (5.13 g) as a white solid by crystallization with ether, mp. 90° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: USRE039419E1uspto-grants-2006_12