Reaktion #94101

ord-4f353ea2a7a64395b4c6d4bfd0269ea2

Reaktionsgleichung

[Cu]
copper
O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Li+].[Li+].[Li+]
lithium citrate
O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-]
citrate
[Li+].[OH-]
lithium hydroxide
→
O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Cu+2].[Li+].[Li+]
Dilithium monocopper(II) citrate

Edukte

[Cu]
copper
O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Li+].[Li+].[Li+]
lithium citrate
—
cupric chloride
O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-]
citrate
[Li+].[OH-]
lithium hydroxide

Reagenzien

Keine

Lösungsmittel

O
water

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeA deep blue solution was formed
  2. 2
    SonstigeThis solution, when evaporated to dryness
  3. 3
    Sonstigegave a deep blue, semicrystalline solid
  4. 4
    Extraktionthe lithium chloride was extracted with 50 milliliters of dry methanol, five times, at 35° C
  5. 5
    Sonstigebehind was evacuated
  6. 6
    Sonstigeto remove methanol
  7. 7
    Sonstigeto crystallize the salt from water-organic solvent systems
  8. 8
    workup.ADDITIONapparently due to the extremely hygroscopic nature of the salt and the high negative charge on the ionized molecule
  9. 9
    Sonstigethe solid obtained

Vorschrift

10 millimoles of lithium citrate were dissolved in 10 milliliters of water. To this solution, 10 millimoles of cupric chloride (CuCl2.2H2O) were added gradually with stirring. A deep blue solution was formed. This was neutralized to a pH of about 7 with 10 millimoles of lithium hydroxide (LiOH.H2O). This solution, when evaporated to dryness, gave a deep blue, semicrystalline solid. This solid was ground to a fine powder and the lithium chloride was extracted with 50 milliliters of dry methanol, five times, at 35° C. The blue solid which remained behind was evacuated to remove methanol and desiccated. An attempt was made to crystallize the salt from water-organic solvent systems, but apparently due to the extremely hygroscopic nature of the salt and the high negative charge on the ionized molecule, the solid obtained was microcrystalline to amorphous. The following formula is proposed for the 1:1 complex of copper and citrate based on elucidation of the structure and analyses described hereinafter.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04129509uspto-grants-1978_12