Reaktion #94072

ord-4782ad1eac23475686430c921bbf4567

Reaktionsgleichung

COC(=O)CC(CSC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)O
Nα -[3-(acetylthio)-2-methoxycarbonylmethylpropanoyl]-L-lysine
COC(=O)CC(CSC(C)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O
Nα -[3-acetylthio-2-methoxycarbonylmethylpropanoyl]-L-arginine
→
NCCCC[C@H](NC(=O)C(CS)CC(N)=O)C(=O)O
Nα -[2-(carbamoylmethyl)-3-mercaptopropanoyl]-L-lysine

Edukte

COC(=O)CC(CSC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)O
Nα -[3-(acetylthio)-2-methoxycarbonylmethylpropanoyl]-L-lysine
COC(=O)CC(CSC(C)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O
Nα -[3-acetylthio-2-methoxycarbonylmethylpropanoyl]-L-arginine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

By substituting Nα -[3-(acetylthio)-2-methoxycarbonylmethylpropanoyl]-L-lysine for the Nα -[3-acetylthio-2-methoxycarbonylmethylpropanoyl]-L-arginine in the procedure of Example 19, Nα -[2-(carbamoylmethyl)-3-mercaptopropanoyl]-L-lysine is obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04128721uspto-grants-1978_12