Reaktion #939026

ord-039741a18ff34bcf95544b62301747df

Reaktionsgleichung

COCCOCCCl
2-chloroethyl 2-methoxyethyl ether
Cc1nc2ccccc2[nH]1
2-methylbenzimidazole
COCCOCCn1c(C)nc2ccccc21
1-[2-(2-Methoxyethoxy)ethyl]-2-methyl-1H-benzimidazole
Ausbeute 78.0%

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

1-[2-(2-Methoxyethoxy)ethyl]-2-methyl-1H-benzimidazole was synthesized as in Synthesis Example 1 except that an equimolar amount of 2-methylbenzimidazole was used instead of benzimidazole and an equimolar amount of 2-chloroethyl 2-methoxyethyl ether was used instead of 2-chloroethyl methyl ether. Yield 78%.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07252925B2uspto-grants-2007_08