Reaktion #939021
ord-7e233837b41f4ef9a3784255f4e715dd
Reaktionsgleichung
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Aufarbeitung
- 1Temperaturwas refluxed for 2 days
- 2Sonstigewater removed from the reaction mixture
- 3SonstigeAfter reaction
- 4Sonstigesolvent was removed in vacuuo
- 5Sonstigeto yield a viscous oil
Vorschrift
A mixture of 1,2,3-propanetricarboxylic acid (25 g), cyclohexanol (55 g), and p-toluenesulfonic acid (100 mg) in toluene (500 mL) was refluxed for 2 days and water removed from the reaction mixture. After reaction was complete, solvent was removed in vacuuo to yield a viscous oil. The crude material was redissolved in heptane and passed through a pad of silica gel to obtain 1,2,3-propanetricarboxylic acid tricyclohexyl ester (50 g) as a pale yellow oil.