Reaktion #939019

Reaktionsgleichung

6-decenoic acid

Methyl 6-bromodecanoate

quinoline

methyl 5-decenoate

methyl 6-decenoate

→

5-decenoic acid

Ausbeute 35.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto react at 240° C. for 5 minutes
2. 2
   Extraktionthe reaction solution was extracted with ether
3. 3
   Waschenwashed with dilute sulfuric acid
4. 4
   Waschenwashed with water
5. 5
   Sonstigedried
6. 6
   Sonstigeevaporated
7. 7
   Sonstigeto remove the solvent
8. 8
   workup.DISTILLATIONdistilled
9. 9
   Sonstigegiving

Vorschrift

Methyl 6-bromodecanoate (1.2 g) and quinoline (1.2g) were mixed together, and then allowed to react at 240° C. for 5 minutes. After the reaction was completed, the reaction solution was extracted with ether, washed with dilute sulfuric acid, washed with water, dried, evaporated to remove the solvent, and then distilled, thereby giving a mixture of methyl 5-decenoate and methyl 6-decenoate (310 mg). The mixture was hydrolyzed in a coventional manner, thereby giving a mixture (270 mg) of 5-decenoic acid and 6-decenoic acid (1/1).

Quelle