Reaktion #936332

ord-b96350cb77e54335852213bc92adb6b9

Reaktionsgleichung

[H][H]
Hydrogen
Cl.N=C1CCCCC(Cc2ccccc2[N+](=O)[O-])N1
product
Cl.N=C1CCCCC(Cc2ccccc2[N+](=O)[O-])N1
hexahydro-7-[(2-nitrophenyl)methyl]-2H-azepin-2-imine, monohydrochloride
→
Cl.Cl.N=C1CCCCC(Cc2ccccc2N)N1
title product
Ausbeute 155.9%
Cl.Cl.N=C1CCCCC(Cc2ccccc2N)N1
2-[(hexahydro-7-imino-1H-azepin-2-yl)methyl]benzenamine, dihydrochloride
Ausbeute 155.9%

Edukte

[H][H]
Hydrogen
Cl.N=C1CCCCC(Cc2ccccc2[N+](=O)[O-])N1
product
Cl.N=C1CCCCC(Cc2ccccc2[N+](=O)[O-])N1
hexahydro-7-[(2-nitrophenyl)methyl]-2H-azepin-2-imine, monohydrochloride

Reagenzien

[Pd]
Palladium on Carbon

Lösungsmittel

CCO
ethanol

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The product of Example 270 (0.150 g, 0.59 mmol) was dissolved in ethanol and treated with 5% Palladium on Carbon under 5 psi of Hydrogen to give the title product (141 mg, 0.46 mmol).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06011028uspto-grants-2000_01