Reaktion #936278

ord-d1da76e72c6c4c9dbbc0ec87f11d4e71

Reaktionsgleichung

COC1=NC(Cc2conc2C(F)(F)F)CCCC1
title product
COC1=NC(Cc2conc2C(F)(F)F)CCCC1
3,4,5,6-tetrahydro-7-methoxy-2-[[3-(trifluoromethyl)isoxazol-4-yl]methyl)-2H-azepine
[Cl-].[NH4+]
ammonium chloride
→
Cl.N=C1CCCCC(Cc2conc2C(F)(F)F)N1
title compound
Cl.N=C1CCCCC(Cc2conc2C(F)(F)F)N1
hexahydro-7-[(3-(trifluoromethyl)isoxazol-4-yl]methyl]-2H-azepin-2-imine, monohydrochloride

Edukte

COC1=NC(Cc2conc2C(F)(F)F)CCCC1
title product
COC1=NC(Cc2conc2C(F)(F)F)CCCC1
3,4,5,6-tetrahydro-7-methoxy-2-[[3-(trifluoromethyl)isoxazol-4-yl]methyl)-2H-azepine
[Cl-].[NH4+]
ammonium chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title product of Example 123 is reacted with ammonium chloride by the method of Example 5 to generate the title compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06011028uspto-grants-2000_01