Reaktion #934835

Reaktionsgleichung

diethylamine hydrochloride

o-nitrobenzenesulfonyl chloride

diethylamine

→

o-nitro-N,N-diethylbenzenesulfonamide

Ausbeute 79.2%

Lösungsmittel

tetrahydrofuran

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigewas removed by filtration
2. 2
   SonstigeThe filtrate was evaporated to dryness in-vacuo
3. 3
   workup.DISSOLUTIONthe residue dissolved in 1-chlorobutane
4. 4
   WaschenThe 1-chlorobutane solution was washed with water
5. 5
   Trocknendried over magnesium sulfate
6. 6
   Sonstigeevaporated in-vacuo

Vorschrift

To a solution of 132.6 g of o-nitrobenzenesulfonyl chloride in 700 ml of tetrahydrofuran was added 88.5 g of diethylamine at 5°-15°. The reaction mixture was stirred at room temperature for 1 hour before the precipitated diethylamine hydrochloride was removed by filtration. The filtrate was evaporated to dryness in-vacuo and the residue dissolved in 1-chlorobutane. The 1-chlorobutane solution was washed with water, dried over magnesium sulfate and evaporated in-vacuo to give 122.4 g of o-nitro-N,N-diethylbenzenesulfonamide as a dark oil.

Quelle