Reaktion #933342

ord-5747d2f0ae0d4eb4b528d7fb280d2d56

Reaktionsgleichung

c1cc(OCC2CO2)ccc1CCOCC1CCC1
1-[4-(2cyclobutylmethoxyethyl)phenoxy]-2,3-epoxypropane
NCCc1ccc(C2=NNC(=O)CC2)cc1
6-[4-(2-aminoethyl)phenyl]-4,5-dihydro-3(2H)-pyridazinone
→
O=C1CCC(c2ccc(CCNCC(O)COc3ccc(CCOCC4CCC4)cc3)cc2)=NN1
6-[4-[2-[3-(4-(2-Cyclobutylmethoxyethyl)phenoxy)-2-hydroxypropylamino]ethyl]phenyl]-4,5-dihydro-3(2H)-pyridazinone

Edukte

c1cc(OCC2CO2)ccc1CCOCC1CCC1
1-[4-(2cyclobutylmethoxyethyl)phenoxy]-2,3-epoxypropane
NCCc1ccc(C2=NNC(=O)CC2)cc1
6-[4-(2-aminoethyl)phenyl]-4,5-dihydro-3(2H)-pyridazinone

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared analogously to Example 1 from 1-[4-(2cyclobutylmethoxyethyl)phenoxy]-2,3-epoxypropane and 6-[4-(2-aminoethyl)phenyl]-4,5-dihydro-3(2H)-pyridazinone.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05135932uspto-grants-1992_08