Reaktion #93196

Reaktionsgleichung

3-(2,2-dibromovinyl)-benzaldehyde

KCN

3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid chloride

→

3-(2,2-Dibromovinyl)-α-cyanobenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

Lösungsmittel

ether

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONthorough mixing
2. 2
   SonstigeThe phases are separated
3. 3
   Extraktionthe aqueous phase is extracted twice
4. 4
   WaschenThe ether solution is washed with sodium bisulfite, NaHCO3 and water
5. 5
   Trocknendried over Na2SO4
6. 6
   Sonstigeevaporated down

Vorschrift

In a two-phase reaction mixture, 6.1 g (0.021 mole) of 3-(2,2-dibromovinyl)-benzaldehyde in 50 ml of ether, 1.5 g (0.023 mole) of KCN in 20 ml of water, 5.0 g (0.022 mole) of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid chloride and 0.5 g of triethylbenzylammonium chloride are stirred at room temperature, and thorough mixing is continued overnight at 25° C. The phases are separated and the aqueous phase is extracted twice by shaking with ether. The ether solution is washed with sodium bisulfite, NaHCO3 and water, dried over Na2SO4 and evaporated down.

Quelle