Reaktion #93192

ord-3b7fd876d48c4b59a8f9ecf5fc329a81

Reaktionsgleichung

CC(=O)SCC(C(=O)OC(=O)C(O)c1ccccc1)c1ccccc1
O-[3-(acetylthio)-2-phenylpropanoyl]mandelic acid
CC(=O)SCCC(=O)O
3-(acetylthio)propanoic acid
O=C(O)C(O)c1ccccc1
mandelic acid
O=C(O)[C@@H](O)Cc1ccccc1
L-3-phenyllactic acid
→
CC(S)(OC(=O)C(O)c1ccccc1)C(=O)c1ccccc1
title compound
CC(S)(OC(=O)C(O)c1ccccc1)C(=O)c1ccccc1
O-(α-Phenyl-β-mercaptopropanoyl)mandelic acid

Edukte

CC(=O)SCC(C(=O)OC(=O)C(O)c1ccccc1)c1ccccc1
O-[3-(acetylthio)-2-phenylpropanoyl]mandelic acid
CC(=O)SCCC(=O)O
3-(acetylthio)propanoic acid
O=C(O)C(O)c1ccccc1
mandelic acid
O=C(O)[C@@H](O)Cc1ccccc1
L-3-phenyllactic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

By substituting 3-(acetylthio)-2-phenylpropanoic acid for 3-(acetylthio)propanoic acid and mandelic acid for L-3-phenyllactic acid in the procedure of Example 5 and then submitting the product to the procedure of Example 6, O-[3-(acetylthio)-2-phenylpropanoyl]mandelic acid and the title compound is obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04611002uspto-grants-1986_09