Reaktion #92931

Reaktionsgleichung

α-bromoisobutyrophenone

1-methylimidazole

→

1-methyl-3-(1,1-dimethyl-2-phenyl-2-oxoethyl)-1H-imidazolium bromide

Ausbeute 63.0%

Lösungsmittel

diethyl ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent was decanted
2. 2
   SonstigeThe solvent was again decanted
3. 3
   workup.DISSOLUTIONthe residue was dissolved in acetonitrile
4. 4
   workup.ADDITIONto adding a small portion of ethyl acetate
5. 5
   FiltrationA white precipitate was collected by filtration
6. 6
   Sonstigerecrystallized from methanol/ethyl acetate

Vorschrift

A solution of 4.6 g (0.02 mol) of α-bromoisobutyrophenone and 1.8 g (0.022 mol) of 1-methylimidazole in 30 ml of diethyl ether was stirred at room temperature for approximately 48 hours. The solvent was decanted and the resulting oil was slurried in ethyl acetate. The solvent was again decanted and the residue was dissolved in acetonitrile prior to adding a small portion of ethyl acetate. A white precipitate was collected by filtration and recrystallized from methanol/ethyl acetate to afford 3.88 g of 1-methyl-3-(1,1-dimethyl-2-phenyl-2-oxoethyl)-1H-imidazolium bromide as glittering white flakes. (63% yield) mp=137°-140° C.

Quelle