Reaktion #9275

Reaktionsgleichung

2-(1-butynyl)pyridine

O-mesitylenesulfonylhydroxyamine

Diethyl ether

→

N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate

Ausbeute 39.1%

Lösungsmittel

dichloromethane

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwhile cooling on ice
2. 2
   Sonstigeto precipitate crystals, which
3. 3
   Filtrationwere collected by filtration
4. 4
   Sonstigedried under reduced pressure

Vorschrift

After dissolving 2-(1-butynyl)pyridine (12.8 g) in dichloromethane (60 mL), a solution of O-mesitylenesulfonylhydroxyamine (Reference document: Synthesis, 1997, 1) (20 g) in dichloromethane (132 mL) was added dropwise while cooling on ice, and the mixture was stirred for 30 minutes. Diethyl ether (2 L) was added to the reaction mixture to precipitate crystals, which were collected by filtration and dried under reduced pressure to obtain N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate (12.6 g) as colorless crystals.

Quelle