Reaktion #92694

Reaktionsgleichung

ethyl 2-(4-cyanophenyl)-2-methylpropanoate

hydrochloric acid

→

ethyl 2-[4-(aminomethyl)phenyl]-2-methylpropanoate hydrochloride

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe catalyst was removed by filtration
2. 2
   Einengenthe filtrate was concentrated under reduced pressure
3. 3
   Sonstigedried

Vorschrift

To a solution of 280 mg of ethyl 2-(4-cyanophenyl)-2-methylpropanoate in 10 ml of ethanol were added 2 mL of 1 M hydrochloric acid and 120 mg of 10% palladium-carbon in this order, followed by stirring for 3 hours under a hydrogen atmosphere at 3 atm. The catalyst was removed by filtration, and the filtrate was concentrated under reduced pressure and dried to obtain 345 mg of, ethyl 2-[4-(aminomethyl)phenyl]-2-methylpropanoate hydrochloride.

Quelle