Reaktion #92471

Reaktionsgleichung

1-bromo-3,5-dinitrobenzene

sodium methoxide

→

1-bromo-3-methoxy-5-nitrobenzene

Ausbeute 65.0%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture was heated
2. 2
   Temperaturto reflux for 12 h
3. 3
   Sonstigequenched with 10% HCl
4. 4
   SonstigeThe solid formed
5. 5
   Filtrationwas filtered
6. 6
   Sonstigedried
7. 7
   Sonstigeto afford the compound in 65% yield (3 g)

Vorschrift

To a solution of 1-bromo-3,5-dinitrobenzene (5 g, 20.2 mmol) in methanol (50 ml) was added sodium methoxide (1.3 g, 24.3 mmol, 1.2 eq.) and the mixture was heated to reflux for 12 h and then quenched with 10% HCl. The solid formed was filtered and dried to afford the compound in 65% yield (3 g).

Quelle