Reaktion #9169

ord-743e272d902a4863a523cebd7ee14efc

Reaktionsgleichung

Cc1cc2ccccc2[nH]1
2-methyl-1H-indole
C[N+](C)=Cc1cccc(Oc2ccccc2)c1.[Cl-]
(3-phenoxy-benzylidene)-dimethylammonium chloride
O=Cc1cccc(Oc2ccccc2)c1
3-phenoxy-benzaldehyde
CNC
dimethylamine
→
Cc1[nH]c2ccccc2c1C(c1cccc(Oc2ccccc2)c1)N(C)C
Dimethyl-[(2-methyl-1H-indol-3-yl)-(3-phenoxy-phenyl)-methyl]-amine

Edukte

Cc1cc2ccccc2[nH]1
2-methyl-1H-indole
C[N+](C)=Cc1cccc(Oc2ccccc2)c1.[Cl-]
(3-phenoxy-benzylidene)-dimethylammonium chloride
O=Cc1cccc(Oc2ccccc2)c1
3-phenoxy-benzaldehyde
CNC
dimethylamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-1H-indole and (3-phenoxy-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 3-phenoxy-benzaldehyde and dimethylamine.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07091220B2uspto-grants-2006_08