Reaktion #91206

Reaktionsgleichung

3-Chloromethyl-2-propylsulfanyl-pyridine

3-chloromethyl-2-propylsulfanyl-pyridine

3-(3,5-difluoro-4-hydroxy-phenyl)-propionic acid ethyl ester

→

title compound

Ausbeute 79.0%

3-[3,5-difluoro-4-(2-propylsulfanyl-pyridin-3-ylmethoxy)-phenyl]-propionic acid ethyl ester

Ausbeute 79.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto react in the same manner as in Step A of Example 1

Vorschrift

3-Chloromethyl-2-propylsulfanyl-pyridine (0.1 g, 0.49 mmol) obtained in Step C of Preparation Example 14 and 3-(3,5-difluoro-4-hydroxy-phenyl)-propionic acid ethyl ester obtained in Step D of Preparation Example 2 were used to react in the same manner as in Step A of Example 1 to obtain the title compound (0.155 g, 79%).

Quelle