Reaktion #91131

ord-32170a2f8df84962a9cc09c372d8ff78

Reaktionsgleichung

O=C(O)c1cccnc1S
2-Mercapto-nicotinic acid
CC(C)CI
isobutyliodide
CC(C)CSc1ncccc1C(=O)O
title compound
Ausbeute 92.0%
CC(C)CSc1ncccc1C(=O)O
2-isobutylsulfanyl-nicotinic acid
Ausbeute 92.0%

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

2-Mercapto-nicotinic acid (2 g, 12.8 mmol) and isobutyliodide were reacted in the same manner as in Step A of Preparation Example 10 to obtain the title compound (2.175 g, 92%).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09447044B2uspto-grants-2016_09