Reaktion #89942

Reaktionsgleichung

2-amino-4-methoxy-5-(2-methoxyethoxyl)benzamide

pyridine

3-nitrobenzoyl chloride

→

desired product

4-Methoxy-5-(2-methoxyethoxy)-(3-nitrophenyl)aminobenzamide

Lösungsmittel

CHCl3

Reaktionsbedingungen

Aufarbeitung

1. 1
   Einengenwas concentrated in vacuo

Vorschrift

To a mixture of 2-amino-4-methoxy-5-(2-methoxyethoxyl)benzamide (1.78 g, 7.40 mmol) and pyridine (2.40 mL, 29.6 mmol) in CHCl3 (40 mL) was added 3-nitrobenzoyl chloride (1.44 g, 7.8 mmol). The mixture was stirred at RT for 2.5 h upon which the mixture was concentrated in vacuo to give the desired product, which was used directly in the next step without purification.

Quelle