Reaktion #89803

ord-d52d89091fb1495d99f897f5da5dbdc4

Reaktionsgleichung

COc1ccc([C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2)cc1O
hesperidin
[Ag]
silver
COc1ccc([C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2)cc1O
hesperidin
[Na+].[OH-]
NaOH
COc1ccc([C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2)cc1O
hesperidin
→
COc1ccc([C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2)cc1O.[Ag]
Hesperidin silver

Edukte

COc1ccc([C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2)cc1O
hesperidin
[Ag]
silver
COc1ccc([C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2)cc1O
hesperidin
[Na+].[OH-]
NaOH
—
silver ion
COc1ccc([C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2)cc1O
hesperidin

Reagenzien

Keine

Lösungsmittel

O
DI water
Cc1ccc(S(=O)(=O)[O-])cc1.[Ag+]
silver p-toluenesulfonate
O
DI water

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    workup.ADDITIONis added
  2. 2
    workup.ADDITIONThe beaker containing the aqueous catalyst solution
  3. 3
    Sonstigeis placed in a 50° C.
  4. 4
    Sonstigefor 12 hours

Vorschrift

Hesperidin/silver colloidal nanoparticle catalyst is prepared by dissolving 1.65 g hesperidin in a beaker containing 800 ml DI water at room temperature. 1 N NaOH solution with stirring is added to adjust the solution pH to 11. In a separate beaker, 2.2 g silver p-toluenesulfonate is dissolved in 60 ml DI water. The silver ion solution is added to the hesperidin solution with strong stirring. The molar ratio of silver to hesperidin is 1:0.34. The beaker containing the aqueous catalyst solution is placed in a 50° C. water bath for 12 hours to test its stability. After 12 hours the solution is observed and no precipitate is expected indicating that the catalyst is still stable.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09441300B2uspto-grants-2016_09