Reaktion #89620

Reaktionsgleichung

Isoprene

dimethyl maleate

→

4-methyl-cyclohex-4-ene-1,2-dicarboxylic acid dimethyl ester

Ausbeute 66.7%

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe autoclave was sealed
2. 2
   TemperaturThe temperature of the autoclave increased to 195° C. due to the
3. 3
   Temperaturheat of the reaction
4. 4
   Sonstigethe completion of the reaction
5. 5
   TemperaturThe autoclave was then cooled to room temperature
6. 6
   workup.DISTILLATIONSimple distillation of the resulting mixture

Vorschrift

Isoprene (350 g, 5.1 mol) and dimethyl maleate (741 g, 5.1 mol) were loaded into a stainless steel autoclave. The autoclave was sealed and heated to 150° C. The temperature of the autoclave increased to 195° C. due to the heat of the reaction. The temperature was held at 160° C. for 1 hour. Gas chromatography (GC) analysis indicated the completion of the reaction. The autoclave was then cooled to room temperature. Simple distillation of the resulting mixture provided 4-methyl-cyclohex-4-ene-1,2-dicarboxylic acid dimethyl ester (725 g, 3.4 mol, 66% yield) as a light yellow liquid.

Quelle