Reaktion #89611

ord-e5d10747c1d04c2695967de07f2120ed

Reaktionsgleichung

CCCC(C)=O
2-Pentanone
CC(C)(CO)CO
2,2-dimethyl-propane-1,3-diol
Cc1ccc(S(=O)(=O)O)cc1
p-toluenesulfonic acid
→
CCCC1(C)OCC(C)(C)CO1
2,5,5-trimethyl-2-propyl-[1,3]dioxane

Edukte

CCCC(C)=O
2-Pentanone
CC(C)(CO)CO
2,2-dimethyl-propane-1,3-diol
Cc1ccc(S(=O)(=O)O)cc1
p-toluenesulfonic acid

Reagenzien

Keine

Lösungsmittel

Cc1ccccc1
toluene

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigeto provide a crude product
  2. 2
    workup.DISTILLATIONDistillation

Vorschrift

2-Pentanone, 2,2-dimethyl-propane-1,3-diol, and a catalytic amount of p-toluenesulfonic acid (PTSA) were refluxed in toluene to provide a crude product. Distillation provided the product 2,5,5-trimethyl-2-propyl-[1,3]dioxane.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09441185B2uspto-grants-2016_09