Reaktion #89604

Reaktionsgleichung

3,4-Dimethyl-pentanal

Dibutylamine

acetic acid

formaldehyde

→

3,4-dimethyl-2-methylene-pentanal

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.WAITaged for another hour
2. 2
   TemperaturThe reaction mixture was cooled down
3. 3
   WaschenThe reaction mixture was sequentially washed with water (2 L), sodium carbonate solution (1 L), and brine (1 L)

Vorschrift

Dibutylamine (34 g), acetic acid (15.78 g), and formaldehyde (230 g) were charged to a reaction flask and heated to 70° C. 3,4-Dimethyl-pentanal (500 g) was fed over 2 hours and aged for another hour. The reaction mixture was cooled down and toluene (200 mL) was added. The reaction mixture was sequentially washed with water (2 L), sodium carbonate solution (1 L), and brine (1 L) to provide the crude product 3,4-dimethyl-2-methylene-pentanal.

Quelle