Reaktion #89103

ord-2450f20f22a4490f8cb23fc37cf78f8b

Reaktionsgleichung

COC(=O)C1CCC(OC)(OC)CN1
methyl 5,5-dimethoxypiperidine-2-carboxylate
Cc1nc(C(=O)O)c(-c2cccc(F)c2)s1
5-(3-fluorophenyl)-2-methylthiazole-4-carboxylic acid
→
COC(=O)C1CCC(OC)(OC)CN1C(=O)c1nc(C)sc1-c1cccc(F)c1
Methyl 1-(5-(3-fluorophenyl)-2-methylthiazole-4-carbonyl)-5,5-dimethoxypiperidine-2-carboxylate

Edukte

COC(=O)C1CCC(OC)(OC)CN1
methyl 5,5-dimethoxypiperidine-2-carboxylate
Cc1nc(C(=O)O)c(-c2cccc(F)c2)s1
5-(3-fluorophenyl)-2-methylthiazole-4-carboxylic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Methyl 1-(5-(3-fluorophenyl)-2-methylthiazole-4-carbonyl)-5,5-dimethoxypiperidine-2-carboxylate was prepared according to general procedure A using product methyl 5,5-dimethoxypiperidine-2-carboxylate and 5-(3-fluorophenyl)-2-methylthiazole-4-carboxylic acid.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09440982B2uspto-grants-2016_09