Reaktion #89093

ord-5723cad4562d4db7bfdd030de86326b0

Reaktionsgleichung

COC(=O)C1CCC(OC)(OC)CN1
methyl 5,5-dimethoxypiperidine-2-carboxylate
Cc1nc(-c2ccccc2)c(C(=O)O)s1
2-methyl-4-phenylthiazole-5-carboxylic acid
→
COC(=O)C1CCC(OC)(OC)CN1C(=O)c1sc(C)nc1-c1ccccc1
Methyl 5,5-dimethoxy-1-(2-methyl-4-phenylthiazole-5-carbonyl)piperidine-2-carboxylate

Edukte

COC(=O)C1CCC(OC)(OC)CN1
methyl 5,5-dimethoxypiperidine-2-carboxylate
Cc1nc(-c2ccccc2)c(C(=O)O)s1
2-methyl-4-phenylthiazole-5-carboxylic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Methyl 5,5-dimethoxy-1-(2-methyl-4-phenylthiazole-5-carbonyl)piperidine-2-carboxylate was prepared according to general procedure A using methyl 5,5-dimethoxypiperidine-2-carboxylate and 2-methyl-4-phenylthiazole-5-carboxylic acid.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09440982B2uspto-grants-2016_09