Reaktion #89083

ord-f64db3501c864ecc94efc4b783550cf4

Reaktionsgleichung

Cc1nc(-c2ccccc2)c(C(=O)N2C(C)CCCC2CN)s1
rac-(2-(aminomethyl)-6-methylpiperidin-1-yl)(2-methyl-4-phenylthiazol-5-yl)methanone
O=C(O)c1cccc2cccnc12
quinoline-8-carboxylic acid
→
Cc1nc(-c2ccccc2)c(C(=O)N2C(C)CCCC2CNC(=O)c2cccc3cccnc23)s1
title compound
Cc1nc(-c2ccccc2)c(C(=O)N2C(C)CCCC2CNC(=O)c2cccc3cccnc23)s1
rac-N-((6-Methyl-1-(2-methyl-4-phenylthiazole-5-carbonyl)piperidin-2-yl)methyl)quinoline-8-carboxamide

Edukte

Cc1nc(-c2ccccc2)c(C(=O)N2C(C)CCCC2CN)s1
rac-(2-(aminomethyl)-6-methylpiperidin-1-yl)(2-methyl-4-phenylthiazol-5-yl)methanone
O=C(O)c1cccc2cccnc12
quinoline-8-carboxylic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared by following the general procedure A using rac-(2-(aminomethyl)-6-methylpiperidin-1-yl)(2-methyl-4-phenylthiazol-5-yl)methanone and quinoline-8-carboxylic acid. MS (ESI) 485 (M+H).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09440982B2uspto-grants-2016_09