Reaktion #88656

Reaktionsgleichung

4-bromo-2-fluoro-1-nitrobenzene

methylamine

→

title compound

5-Bromo-N-methyl-2-nitroaniline

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationthe resulting precipitate was collected by filtration
2. 2
   Waschenwashed with ice-
3. 3
   Temperaturcooled ethanol and diisopropyl ether
4. 4
   SonstigeThe obtained solid was dried

Vorschrift

To a solution of 4-bromo-2-fluoro-1-nitrobenzene (25 g) in ethanol (100 mL) was added methylamine (40% in methanol, 34.8 mL) at room temperature, and the mixture was stirred for 1 hr. The obtained mixture was cooled to 0° C., and the resulting precipitate was collected by filtration and washed with ice-cooled ethanol and diisopropyl ether. The obtained solid was dried to give the title compound (24.8 g) as a yellow solid.

Quelle