Reaktion #88173

ord-dc18719ab1344ca4953750613a60c359

Reaktionsgleichung

COC(=O)c1cc(C)cc(C#N)c1
methyl 3-cyano-5-methylbenzoate
COC(=O)c1cc(CN)cc(OC)c1.Cl
Intermediate 2
COC(=O)c1cc(CN)cc(OC)c1.Cl
Methyl 3-(aminomethyl)-5-methoxybenzoate hydrochloride
→
COC(=O)c1cc(C)cc(CN)c1.Cl
Methyl 3-(aminomethyl)-5-methylbenzoate hydrochloride

Edukte

COC(=O)c1cc(C)cc(C#N)c1
methyl 3-cyano-5-methylbenzoate
COC(=O)c1cc(CN)cc(OC)c1.Cl
Intermediate 2
COC(=O)c1cc(CN)cc(OC)c1.Cl
Methyl 3-(aminomethyl)-5-methoxybenzoate hydrochloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Methyl 3-(aminomethyl)-5-methylbenzoate hydrochloride was prepared from methyl 3-cyano-5-methylbenzoate in an analogous manner to Intermediate 2.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09440949B2uspto-grants-2016_09