Reaktion #88115

Reaktionsgleichung

1-(4-methoxy-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole

intermediate G

1-(4-methoxy-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole

2-(3-fluoro-phenyl)-acetonitrile

→

title compound

3-(3-Fluoro-phenyl)-5-[2-(4-methoxy-phenyl)-2H-pyrazol-3-yl]-benzo[c]isoxazole

Reaktionsbedingungen

Vorschrift

The title compound, light green solid (81 mg, 62%), MS (ISP) m/z=386.2 [(M+H)+], mp 203° C., was prepared in accordance with the general method of example 1 from 1-(4-methoxy-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole (intermediate G) (100 mg, 353 μmol) and commercially available 2-(3-fluoro-phenyl)-acetonitrile.

Quelle