Reaktion #88103

Reaktionsgleichung

1-(3-fluoro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole

intermediate D

1-(3-fluoro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole

2-(4-fluoro-phenyl)-acetonitrile

→

title compound

3-(4-Fluoro-phenyl)-5-[2-(3-fluoro-phenyl)-2H-pyrazol-3-yl]-benzo[c]isoxazole

Reaktionsbedingungen

Vorschrift

The title compound, light grey solid (74 mg, 56%), MS (ISP) m/z=374.1 [(M+H)+], mp 175° C., was prepared in accordance with the general method of example 1 from 1-(3-fluoro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole (intermediate D) (100 mg, 353 μmol) and commercially available 2-(4-fluoro-phenyl)-acetonitrile.

Quelle