Reaktion #87514

Reaktionsgleichung

2-chloro-6-fluorobenzamide

oxalyl chloride

→

desired product

2-chloro-6-fluorobenzoyl isocyanate

Lösungsmittel

EDC

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe reaction mass was refluxed for 24 h
2. 2
   SonstigeExcess of solvent was removed under vacuum

Vorschrift

To a solution of 2-chloro-6-fluorobenzamide (2.0 g, 0.011 mmol) in EDC (10 mL) was added oxalyl chloride (2.18 g, 0.017 mmol). The reaction mass was refluxed for 24 h. Excess of solvent was removed under vacuum to afford 2.0 g of desired product.

Quelle