Reaktion #8726

Reaktionsgleichung

2-chloro-5-nitrophenol

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2-Chloro-5-aminophenol

Lösungsmittel

ethyl acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe mixture was filtered through Celite®
2. 2
   Waschenthe residue washed well with ethyl acetate
3. 3
   SonstigeEvaporation of the ethyl acetate
4. 4
   Sonstigegave a solid (95 g, 100% crude yield) which

Vorschrift

A solution of 2-chloro-5-nitrophenol (114 g, 0.66 mol) in ethyl acetate (500 mL) was treated with 5% Pt/C (510 mg, 0.5 weight %) and the mixture shaken under a hydrogen atmosphere (30 psi) for 6 h. The mixture was filtered through Celite® and the residue washed well with ethyl acetate. Evaporation of the ethyl acetate gave a solid (95 g, 100% crude yield) which was taken directly into the next step.

Quelle