Reaktion #86300

Reaktionsgleichung

N-benzenesulfonyl-D,L-leucyl-L-proline benzyl ester

hydrogen

→

solid

Ausbeute 99.6%

N-benzenesulfonyl-D,L-leucyl-L-proline

Ausbeute 99.6%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto react at room temperature for 3 h
2. 2
   Filtrationfiltered
3. 3
   Einengenconcentrated under reduced pressure
4. 4
   Sonstigeto remove the solvent

Vorschrift

N-benzenesulfonyl-D,L-leucyl-L-proline benzyl ester (2 g) was dissolved in methanol (40 ml), and 10% palladium-carbon (200 mg) was added. The resulting mixture aerated with hydrogen was allowed to react at room temperature for 3 h, filtered and concentrated under reduced pressure to remove the solvent to give a white foam-like solid (1.6 g, 99%), which was directly used for the next reaction.

Quelle