Reaktion #85018

ord-9c6f7f7830724d2fbc1dc0224f6e5330

Reaktionsgleichung

COc1cc(-c2cc(Cl)ccc2[N+](=O)[O-])c(OC)cn1
4-(5-chloro-2-nitrophenyl)-2,5-dimethoxypyridine
Cl.c1cc[nH+]cc1
pyridinium hydrochloride
→
COc1c[nH]c(=O)cc1-c1cc(Cl)ccc1[N+](=O)[O-]
4-(5-Chloro-2-nitrophenyl)-5-methoxypyridin-2(1H)-one

Edukte

COc1cc(-c2cc(Cl)ccc2[N+](=O)[O-])c(OC)cn1
4-(5-chloro-2-nitrophenyl)-2,5-dimethoxypyridine
Cl.c1cc[nH+]cc1
pyridinium hydrochloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

124 mg (purity 93%, 0.39 mmol) of 4-(5-chloro-2-nitrophenyl)-2,5-dimethoxypyridine and pyridinium hydrochloride were reacted according to General Method 3A. Yield: 115 mg (purity 85%, 89% of theory)

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09434690B2uspto-grants-2016_09