Reaktion #84935

Reaktionsgleichung

4-iodopyridin-2(1H)-one

ethyl 2-bromohexanoate

sodium hydride

lithium bromide

→

Ethyl 2-(4-iodo-2-oxopyridin-1(2H)-yl)hexanoate

Reaktionsbedingungen

Vorschrift

500 mg (2.3 mmol) of 4-iodopyridin-2(1H)-one and 706 mg (3.2 mmol) of ethyl 2-bromohexanoate (racemate) in the presence of 1.15 eq. of sodium hydride and 2.3 eq. of lithium bromide were reacted according to General Method 4C. Yield: 352 mg (43% of theory)

Quelle