Reaktion #84848

Reaktionsgleichung

2-(4-bromo-3,5-dimethoxyphenyl)furan

N,2-dimethoxy-N-methyl-2-(4-(pyrazin-2-yl)phenyl)acetamide

→

1-(5-(4-Bromo-3,5-dimethoxyphenyl)furan-2-yl)-2-methoxy-2-(4-(pyrazin-2-yl)phenyl)ethanone

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigePurification by chromatography (60% EtOAc/hexanes)

Vorschrift

1-(5-(4-Bromo-3,5-dimethoxyphenyl)furan-2-yl)-2-methoxy-2-(4-(pyrazin-2-yl)phenyl)ethanone was prepared from 2-(4-bromo-3,5-dimethoxyphenyl)furan and N,2-dimethoxy-N-methyl-2-(4-(pyrazin-2-yl)phenyl)acetamide according to the procedure used in Example 30. Purification by chromatography (60% EtOAc/hexanes) gave the product as a pale yellow solid (0.060 g, 17% yield). MS: m/z 509.3 [M+H]+.

Quelle