Reaktion #84760

Reaktionsgleichung

sodium sulfate

2-amino-4-methoxybenzaldehyde

N-bromosuccinimide

→

title compound

Ausbeute 56.0%

2-amino-5-bromo-4-methoxybenzaldehyde

Ausbeute 56.0%

Lösungsmittel

dichloromethane

water

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationfiltered
2. 2
   Einengenconcentrated

Vorschrift

To a stirred solution of 2-amino-4-methoxybenzaldehyde (6 g, 39.7 mmol) in dichloromethane (100 mL) was added N-bromosuccinimide (7 g, 39.7 mmol). The reaction mixture was diluted with dichloromethane and water. The separated organic layer was dried sodium sulfate, filtered and concentrated to give the title compound (5 g, 56%) as a yellow solid. MS (ES+) C8H8BrNO2 requires: 229, 231, found: 230, 232 [M+H]+.

Quelle