Reaktion #84150

Reaktionsgleichung

3-(4-Nitro-pyrazol-1-yl)-propan-1-ol

→

title compound

Ausbeute 101.6%

3-(4-Amino-pyrazol-1-yl)-propan-1-ol

Ausbeute 101.6%

Lösungsmittel

MeOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe reaction mixture was filtered
2. 2
   Sonstigethe solvent evaporated in vacuo

Vorschrift

3-(4-Nitro-pyrazol-1-yl)-propan-1-ol (1.41 g, 8.23 mmol) was dissolved in MeOH (15 mL). Pd/C (0.532 g, 0.82 mmol) was added and the mixture was stirred under H2 at rt for 16 hours. The reaction mixture was filtered and the solvent evaporated in vacuo to afford the title compound as a red/brown oil (1.18 g, 100%); LCMS, Rt=0.31 min (MeOH-FA method), m/z 142 (MH+).

Quelle